SCHEMBL10786261

SCHEMBL10786261

COC1=CC(=O)C(c2ccccc2)=CC1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.55
PDE4B Q07343 2/20 0.54
KDM4E B2RXH2 3/20 0.51
MEN1 O00255 3/20 0.51
MAPT P10636 3/20 0.51
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 2/20 0.51
TP53 P04637 2/20 0.51
CYP3A4 P08684 2/20 0.51
HPGD P15428 2/20 0.51
ALOX15 P16050 2/20 0.51
HSD17B10 Q99714 2/20 0.51
THRB P10828 1/20 0.51
BLM P54132 1/20 0.51
PTPN1 P18031 5/20 0.49
ALOX5 P09917 1/20 0.47
CDC25B P30305 2/20 0.47
IDO1 P14902 1/20 0.47
CDC25A P30304 1/20 0.47
MAOA P21397 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221295 0.81 BACE1 (0.65) BACE1PDE4BMAPTALDH1A1HPGD
SCHEMBL11253658 0.80 BACE1 (0.45) BACE1PDE4BMEN1MAPTKMT2A
SCHEMBL10446587 0.80 PTPRC (0.51) BACE1PDE4BKDM4EMEN1MAPT
SCHEMBL49737 0.76 ERBB2 (0.62) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL25834271 0.74 BACE1 (0.53) BACE1PDE4BMEN1MAPTKMT2A
SCHEMBL28856262 0.73 ERBB2 (0.59) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL28259188 0.73 ERBB2 (0.59) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL10446708 0.73 MAOB (0.44) BACE1PDE4BKMT2APTPN1CDC25B
SCHEMBL12480578 0.71 BACE1 (0.60) BACE1PDE4BMAPTALDH1A1HPGD
SCHEMBL22203772 0.71 BACE1 (0.55) BACE1PDE4BMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789307-B2 Colorant filter, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-10-17 US disclosed
US-11733435-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20230012898-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-01-19 US disclosed
WO-2021162115-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-08-19 WO disclosed
US-20210026199-A1 COLORANT FILTER, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-01-28 US disclosed
US-20210005673-A1 COLOR CORRECTION FILTER FOR WHITE ORGANIC ELECTROLUMINESCENT LIGHT SOURCE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-01-07 US disclosed
US-20200217993-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-07-09 US disclosed
EP-0144580-B1 TRIPHENDIOXAZINE DYES BAYER AG (DE) 1987-07-08 EP disclosed
US-4591643-A Triphendioxazine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1986-05-27 US disclosed
EP-0144580-A2 Triphendioxazine dyes BAYER AG (DE) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230012898-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE EPCAM, ICAM1, STRA6 BACE1 4368/4885PDE4B 2953/4885KDM4E 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.