SCHEMBL25834271

SCHEMBL25834271

CC1=CC(=O)C(c2ccccc2)=CC1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 7/20 0.53
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
PTPN1 P18031 4/20 0.48
CDC25B P30305 2/20 0.48
PTPRC P08575 1/20 0.48
PTPRF P10586 1/20 0.48
HSD17B3 P37058 1/20 0.48
PDE4B Q07343 1/20 0.46
ALDH1A1 P00352 3/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
GAA P10253 2/20 0.42
MEN1 O00255 1/20 0.42
PLIN1 O60240 1/20 0.42
NR1I2 O75469 1/20 0.42
USP2 O75604 1/20 0.42
GSR P00390 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221295 0.86 BACE1 (0.65) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL25834276 0.83 BACE1 (0.50) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL25834719 0.81 BACE1 (0.48) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL14507718 0.78 PLK1 (0.50) BACE1MAOAMAOBCDC25BALDH1A1
SCHEMBL12480578 0.76 BACE1 (0.60) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL22203772 0.76 BACE1 (0.55) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL11622324 0.74 BACE1 (0.53) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL11229393 0.74 BACE1 (0.53) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL8749720 0.74 BACE1 (0.53) BACE1MAOAMAOBPTPN1CDC25B
SCHEMBL10786261 0.74 BACE1 (0.55) BACE1MAOAMAOBPTPN1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789307-B2 Colorant filter, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-10-17 US disclosed
US-11733435-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20230227393-A1 IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES THE UNIVERSITY OF HONG KONG (CN) 2023-07-20 US disclosed
US-20230227393-A1 IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES THE UNIVERSITY OF HONG KONG (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227393-A1 IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES NFE2L2, DUOX1, DUOX2 BACE1 608/4885MAOA 44/4885MAOB 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.