Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49737 | 0.97 | ERBB2 (0.62) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL28259188 | 0.94 | ERBB2 (0.59) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL3417111 | 0.84 | HKDC1 (0.56) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| Coprinin SCHEMBL3416504 | 0.84 | ERBB2 (0.50) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL23751954 | 0.82 | ERBB2 (0.48) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL17261224 | 0.82 | ERBB2 (0.48) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL30092600 | 0.78 | ERBB2 (0.45) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL11229232 | 0.78 | ERBB2 (0.45) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL16520808 | 0.77 | ERBB2 (0.43) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL11025815 | 0.75 | MAPT (0.50) | ERBB2HKDC1KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107551089-B | A kind of medicine for treating hyperlipidemia and preparation method thereof and detection method | 新疆阿勒泰地区哈萨克医医院 | 2018-05-04 | — | — | CN | disclosed |
| CN-107551089-A | A kind of medicine for treating hyperlipidemia and preparation method thereof and detection method | 新疆阿勒泰地区哈萨克医医院 | 2018-01-09 | — | — | CN | disclosed |