Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1078545 | 0.95 | SLC2A1 (0.50) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL16390769 | 0.90 | SLC2A1 (0.58) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL16390920 | 0.90 | SLC2A1 (0.53) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL2682252 | 0.87 | SLC2A1 (0.51) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL16390740 | 0.85 | SLC2A1 (0.51) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL16390787 | 0.85 | SLC2A1 (0.48) | SLC2A1MAP4K4METGRK5 | |
| SCHEMBL16390901 | 0.84 | SLC2A1 (0.49) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL2681696 | 0.83 | SLC2A1 (0.59) | SLC2A1CDK1CDK2MKNK1MKNK2 | |
| Trifluoroacetic Acid SCHEMBL2681709 | 0.82 | MET (0.51) | SLC2A1MAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL1078038 | 0.81 | MET (0.49) | SLC2A1METMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454253-B1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GMBH (DE) | 2015-01-21 | — | — | EP | claimed |
| EP-2454253-B1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GMBH (DE) | 2015-01-21 | — | — | EP | disclosed |
| EP-2454253-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | Merck Patent GmbH (DE) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006567-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | disclosed |