Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986412 | 0.98 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBGLATSHR | |
| SCHEMBL2416341 | 0.83 | L3MBTL1 (0.56) | L3MBTL1FKBP1APOLBGLATSHR | |
| SCHEMBL8402970 | 0.83 | ALDH1A1 (0.51) | L3MBTL1POLBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL14010813 | 0.83 | — | — | |
| SCHEMBL14654219 | 0.82 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBGLATSHR | |
| SCHEMBL14223107 | 0.79 | L3MBTL1 (0.51) | L3MBTL1FKBP1APOLBGLATSHR | |
| SCHEMBL944668 | 0.79 | ALDH1A1 (0.53) | L3MBTL1TSHRALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL11406691 | 0.79 | — | — | |
| SCHEMBL23135854 | 0.78 | GLA (0.62) | L3MBTL1FKBP1APOLBGLATSHR | |
| SCHEMBL14446152 | 0.78 | L3MBTL1 (0.66) | L3MBTL1FKBP1APOLBGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687844-A | Process for the direct preparation of N,N-disubstituted derivatives for 4,13-diaza-18-crown-6 | UNIVERSITY OF MARYLAND (US) | 1987-08-18 | — | — | US | claimed |
| US-4687844-A | Process for the direct preparation of N,N-disubstituted derivatives for 4,13-diaza-18-crown-6 | UNIVERSITY OF MARYLAND (US) | 1987-08-18 | — | — | US | disclosed |
| US-4597903-A | Process for the direct preparation of N,N-disubstituted derivatives for 4,13-diaza-18-crown-6 | UNIVERSITY OF MARYLAND (US) | 1986-07-01 | — | — | US | disclosed |