Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783997 | 0.91 | MAPT (0.47) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10783350 | 0.88 | RAB9A (0.48) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10781778 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11244669 | 0.81 | RORC (0.55) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11243986 | 0.81 | RORC (0.64) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11229846 | 0.81 | IL2 (0.46) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL13814849 | 0.78 | MAPT (0.55) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10790426 | 0.77 | MAPT (0.54) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10786517 | 0.77 | NPC1 (0.43) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8659704 | 0.77 | MEN1 (0.63) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116728-B1 | COMPOSITION ACTIVE AGAINST MITES, WHITEFLY AND THRIPS, PHARMACEUTICAL COMPOSITION, AND NEW BENZOYLUREAU COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-08-12 | — | — | EP | disclosed |