SCHEMBL10787147

SCHEMBL10787147

CC1CCC2C(=O)N(CCCN3CCN(c4ncccn4)CC3)C(=O)C2C1

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.61
HTR1A P08908 1/20 0.61
DRD4 P21917 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10836571 0.98 DRD2 (0.65) DRD2HTR1ADRD4
Hydrochloric Acid SCHEMBL10786953 0.97 DRD2 (0.65) DRD2HTR1ADRD4
SCHEMBL10835599 0.91 DRD2 (0.69) DRD2HTR1ADRD4
SCHEMBL10788356 0.88 DRD2 (0.63) DRD2HTR1ADRD4
SCHEMBL10836726 0.88 DRD2 (0.73) DRD2HTR1ADRD4
Hydrochloric Acid SCHEMBL10836083 0.87 DRD2 (0.73) DRD2HTR1ADRD4
SCHEMBL10784007 0.86 DRD2 (0.67) DRD2HTR1ADRD4
SCHEMBL9589567 0.86 DRD2 (0.67) DRD2HTR1ADRD4
SCHEMBL10835049 0.86 HTR1A (0.58) DRD2HTR1ADRD4
SCHEMBL10786864 0.86 HTR2A (0.58) DRD2HTR1ADRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0109562-B1 SUCCINIMIDE DERIVATIVES AND THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP disclosed
US-4598078-A N-(substituted piperazinyl) alkylbicyclic succinimide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-07-01 US disclosed
EP-0109562-A1 Succinimide derivatives and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-30 EP disclosed