Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784053 | 0.98 | HTR1A (0.65) | HTR1ASIGMAR1DRD2DRD4 | |
| SCHEMBL10783585 | 0.86 | DRD2 (0.66) | HTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10784027 | 0.85 | DRD2 (0.67) | HTR1ADRD2DRD4 | |
| SCHEMBL10835049 | 0.84 | HTR1A (0.58) | HTR1ASIGMAR1DRD2DRD4 | |
| SCHEMBL10781927 | 0.84 | DRD2 (0.70) | HTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10782020 | 0.82 | DRD2 (0.70) | HTR1ADRD2DRD4 | |
| SCHEMBL10787025 | 0.82 | DRD2 (0.68) | HTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10787472 | 0.81 | DRD2 (0.69) | HTR1ADRD2DRD4 | |
| SCHEMBL10835599 | 0.81 | DRD2 (0.69) | HTR1ADRD2DRD4 | |
| SCHEMBL10786683 | 0.81 | DRD2 (0.65) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109562-B1 | SUCCINIMIDE DERIVATIVES AND THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4598078-A | N-(substituted piperazinyl) alkylbicyclic succinimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-01 | — | — | US | disclosed |