Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56520 | 0.93 | CA2 (0.59) | CA2TAAR1TDP1PTGS1PTGS2 | |
| SCHEMBL7719756 | 0.87 | CA2 (0.65) | CA2TDP1CA12CA1CA4 | |
| SCHEMBL6546 | 0.86 | MAOB (0.59) | CA2TAAR1TDP1PTGS1PTGS2 | |
| SCHEMBL11129547 | 0.82 | CA2 (0.48) | CA2TAAR1TDP1PTGS1PTGS2 | |
| SCHEMBL16561361 | 0.82 | IDO1 (0.58) | TAAR1TDP1MAOBIDO1LOXL2 | |
| SCHEMBL1468357 | 0.82 | IDO1 (0.58) | TAAR1TDP1MAOBIDO1LOXL2 | |
| SCHEMBL9107231 | 0.80 | LTA4H (0.51) | CA2TAAR1TDP1MAOBKDM4E | |
| Hydrochloric Acid SCHEMBL7941845 | 0.79 | IDO1 (0.55) | TAAR1TDP1MAOBIDO1LOXL2 | |
| SCHEMBL40656 | 0.79 | CA2 (0.77) | CA2TAAR1TDP1CA12CA1 | |
| SCHEMBL4228481 | 0.79 | CA2 (0.50) | CA2TAAR1TDP1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112588-B1 | 4-HYDROXY-ALPHA-ETHYL BENZHYDROLES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-11-11 | — | — | EP | claimed |
| EP-0112588-A2 | 4-Hydroxy-alpha-ethyl benzhydroles, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | claimed |
| EP-0112588-B1 | 4-HYDROXY-ALPHA-ETHYL BENZHYDROLES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-11-11 | — | — | EP | disclosed |
| EP-0112588-A2 | 4-Hydroxy-alpha-ethyl benzhydroles, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |