Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383936 | 0.83 | MEN1 (0.39) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL17745050 | 0.75 | CASP3 (0.37) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL15039274 | 0.73 | KDR (0.38) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL15020242 | 0.71 | KDR (0.34) | MEN1APAF1CASP3KMT2APAX8 | |
| Acetic Acid SCHEMBL11844797 | 0.65 | KDM4E (0.33) | GAAKDM4E | |
| SCHEMBL6815196 | 0.64 | MEN1 (0.51) | MEN1KMT2AGAAKDM4E | |
| SCHEMBL11789530 | 0.64 | BRD4 (0.47) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL11787303 | 0.63 | POLB (0.37) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL1225409 | 0.62 | POLB (0.61) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL29666518 | 0.62 | POLB (0.61) | MEN1KMT2APOLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675130-A | HAIR DYES | L'OREAL (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4246181-A | HAIR DYE | L'OREAL (FR) | 1981-01-20 | — | — | US | disclosed |