Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815196 | 0.69 | MEN1 (0.51) | KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL10787660 | 0.65 | MEN1 (0.37) | KDM4EGAA | |
| SCHEMBL11785259 | 0.65 | MEN1 (0.39) | KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL11788889 | 0.64 | PTK2 (0.42) | GAAMAPTPKMALDH1A1 | |
| SCHEMBL5475142 | 0.63 | MEN1 (0.66) | KDM4EMAPTALDH1A1 | |
| SCHEMBL22691985 | 0.62 | ALDH1A1 (0.58) | KDM4EGAAMAPTPKMALDH1A1 | |
| SCHEMBL11470823 | 0.62 | KDM4E (0.51) | KDM4EMAPTALDH1A1 | |
| SCHEMBL24405268 | 0.61 | ALDH1A1 (0.48) | KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL11789530 | 0.61 | BRD4 (0.47) | KDM4EGAAMAPTPKMALDH1A1 | |
| SCHEMBL20632141 | 0.60 | LMNA (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997546-A | HAIR DYE | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-12-14 | — | — | US | claimed |