Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367544 | 0.85 | TSHR (0.47) | KDM4ETSHRHSD17B10NPSR1HPGD | |
| SCHEMBL9363842 | 0.84 | KMT2A (0.47) | TSHRHSD17B10KMT2AMEN1NPSR1 | |
| SCHEMBL8984936 | 0.82 | HSP90AA1 (0.46) | KDM4EGAATSHRHSD17B10NPSR1 | |
| SCHEMBL10786897 | 0.80 | ADORA3 (0.52) | KDM4EGAATSHRHSD17B10KMT2A | |
| SCHEMBL8438113 | 0.77 | HPGD (0.60) | KDM4EGAATSHRHSD17B10NPSR1 | |
| SCHEMBL8442358 | 0.77 | TSHR (0.45) | KDM4EGAATSHRHSD17B10KMT2A | |
| SCHEMBL9691613 | 0.77 | ADORA3 (0.49) | KDM4EGAATSHRHSD17B10KMT2A | |
| SCHEMBL5363492 | 0.76 | TSHR (0.74) | KDM4EGAATSHRHSD17B10KMT2A | |
| SCHEMBL9343265 | 0.76 | MAPT (0.53) | KDM4EGAATSHRHSD17B10KMT2A | |
| SCHEMBL9363808 | 0.76 | HSP90AA1 (0.42) | KDM4EGAATSHRHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110073-B1 | PROCESS FOR THE PREPARATION OF TETRAHYDROPYRIDINES | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |