SCHEMBL1078779

SCHEMBL1078779

C=CC(N)c1cccc2c1Nc1ccccc1S2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.46
MAPT P10636 7/20 0.46
GAA P10253 6/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
SNCA P37840 3/20 0.46
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX12 P18054 1/20 0.46
MAOA P21397 1/20 0.46
CNR1 P21554 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11022635 0.82 NOX1 (0.46) NOX1MAPTGAAMEN1KMT2A
SCHEMBL8966024 0.77 NOX1 (0.46) NOX1MAPTGAAMEN1KMT2A
SCHEMBL28909424 0.76 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL8749550 0.76 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL19747564 0.74 NOX1 (0.46) NOX1MAPTGAAMEN1KMT2A
Iodide SCHEMBL13386087 0.74 NOX1 (0.50) NOX1MAPTGAAMEN1KMT2A
SCHEMBL1767892 0.73 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL13386127 0.72 NOX1 (0.47) NOX1MAPTGAAMEN1KMT2A
SCHEMBL22686160 0.72 NOX1 (0.47) NOX1MAPTGAAMEN1KMT2A
SCHEMBL885279 0.72 NOX1 (0.47) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659772-B1 Multifunctional viscosity index improvers DSM COPOLYMER INC (US) 1998-09-09 EP claimed
EP-0510991-B1 Multifunctional viscosity index improver ETHYL ADDITIVES CORP (US) 1997-03-05 EP claimed
EP-0659772-A1 Multifunctional viscosity index improvers TEXACO DEVELOPMENT CORPORATION (US) 1995-06-28 EP claimed
US-5424366-A Graft polymerization of an addition polymer with a monomer prepared by an aminoalkyl phenothiazine and an unsaturated compound containing a reactive group to form an additive for engine lubricates TEXACO INC. (US) 1995-06-13 US claimed
US-5200100-A For lubricating oils; ethylene, propylene (and norborndiene) copolymer grafted with unsaturated functional monomer TEXACO INC. (US) 1993-04-06 US claimed
EP-0510991-A1 Multifunctional viscosity index improver TEXACO DEVELOPMENT CORPORATION (US) 1992-10-28 EP claimed
US-20230332065-A1 LUBRICATING COMPOSITION AND METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE THE LUBRIZOL CORPORATION (US) 2023-10-19 US disclosed
US-20230323234-A1 LUBRICATING COMPOSITION AND METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE THE LUBRIZOL CORPORATION (US) 2023-10-12 US disclosed
CN-110997882-B Lubricating composition containing self-assembled polymethacrylate block copolymer and ethylene-alpha-olefin copolymer 路博润公司 2023-08-08 CN disclosed
EP-3116980-B1 METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE LUBRIZOL CORP (US) 2023-04-26 EP disclosed
EP-3851508-B1 METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE LUBRIZOL CORP (US) 2022-12-28 EP disclosed
US-11365367-B2 Lubricating composition for and method of lubricating an internal combustion engine THE LUBRIZOL CORPORATION (US) 2022-06-21 US disclosed
US-11359159-B2 Lubricating composition containing a self-assembling polymethacrylate block copolymer and an ethylene-α-olefin copolymer THE LUBRIZOL CORPORATION (US) 2022-06-14 US disclosed
EP-0818525-A2 Branched polyolefin polymers as additives in fuel and lubricating oil compositions DSM Copolymer, Inc. (US) 1998-01-14 EP disclosed
EP-0510991-B1 Multifunctional viscosity index improver ETHYL ADDITIVES CORP (US) 1997-03-05 EP disclosed
EP-0659772-A1 Multifunctional viscosity index improvers TEXACO DEVELOPMENT CORPORATION (US) 1995-06-28 EP disclosed
US-5424366-A Graft polymerization of an addition polymer with a monomer prepared by an aminoalkyl phenothiazine and an unsaturated compound containing a reactive group to form an additive for engine lubricates TEXACO INC. (US) 1995-06-13 US disclosed
US-5275746-A Multifunctional viscosity index improver containing phenothiazine TEXACO INC. (US) 1994-01-04 US disclosed
US-5200100-A For lubricating oils; ethylene, propylene (and norborndiene) copolymer grafted with unsaturated functional monomer TEXACO INC. (US) 1993-04-06 US disclosed
EP-0510991-A1 Multifunctional viscosity index improver TEXACO DEVELOPMENT CORPORATION (US) 1992-10-28 EP disclosed