SCHEMBL1767892

SCHEMBL1767892

C=Cc1cccc2c1Nc1ccccc1S2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.53
MAPT P10636 7/20 0.53
GAA P10253 6/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
SNCA P37840 3/20 0.53
BCHE P06276 2/20 0.53
ACHE P22303 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ALOX15 P16050 2/20 0.53
CYP1A2 P05177 1/20 0.53
POLB P06746 1/20 0.53
CYP3A4 P08684 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
ALOX12 P18054 1/20 0.53
MAOA P21397 1/20 0.53
CNR1 P21554 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
HTR2C P28335 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6005188 0.83 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL290727 0.83 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL30537318 0.83 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL112298 0.83 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL988099 0.79 NOX1 (0.48) NOX1MAPTGAAMEN1KMT2A
SCHEMBL30957952 0.79 NOX1 (0.48) NOX1MAPTGAAMEN1KMT2A
SCHEMBL988100 0.79 NOX1 (0.48) NOX1MAPTGAAMEN1KMT2A
SCHEMBL30274184 0.77 NOX1 (0.67) NOX1MAPTGAAMEN1KMT2A
SCHEMBL10530491 0.77 NOX1 (0.67) NOX1MAPTGAAMEN1KMT2A
SCHEMBL290846 0.77 NOX1 (0.59) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232089-A Vinylphenol thiazine fluorescent probe and preparation method and application thereof 洛阳师范学院 2022-10-25 CN claimed
EP-2501726-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER Castrol Limited (GB) 2012-09-26 EP claimed
WO-2011062914-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER CASTROL LIMITED (GB) 2011-05-26 WO claimed
US-20050154042-A1 N-alkyl pyrroles as HMG-CoA reductase inhibitors WARNER-LAMBERT COMPANY 2005-07-14 US claimed
US-4389474-A Thiopyrylium compounds and photoconductive compositions containing said compounds FUJI PHOTO FILM CO., LTD. (JP) 1983-06-21 US claimed
US-3999989-A SALTS OF INDOLINE SPIROBENZOPYRANS FUJI PHOTO FILM CO., LTD. (JA) 1976-12-28 US claimed
CN-115232089-B Vinyl phenol thiazine fluorescent probe and preparation method and application thereof 洛阳师范学院 2024-11-15 CN disclosed
US-20240010624-A1 TRICYCLIC COMPOUNDS AND RELATED COMPOSITIONS, ZINC ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS ALIONYX ENERGY SYSTEMS 2024-01-11 US disclosed
CN-115232089-A Vinylphenol thiazine fluorescent probe and preparation method and application thereof 洛阳师范学院 2022-10-25 CN disclosed
WO-2022109329-A1 TRICYCLIC COMPOUNDS AND RELATED COMPOSITIONS, ZINC ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS ALIONYX ENERGY SYSTEMS (US) 2022-05-27 WO disclosed
WO-2017064033-A1 UV CURABLE INKJET INKS AGFA GRAPHICS NV (BE) 2017-04-20 WO disclosed
CN-106459631-A Aqueous resin based ink jet inks 爱克发印艺公司 2017-02-22 CN disclosed
CN-106459630-A Aqueous resin based inkjet inks 爱克发印艺公司 2017-02-22 CN disclosed
EP-0316446-A4 IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD 1991-03-20 EP disclosed
US-4886626-A REDUCTION OF ELECTRICAL RESISTANCE CREST-FOAM CORPORATION (US) 1989-12-12 US disclosed
EP-0316446-A1 IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD CREST-FOAM Corp. (US) 1989-05-24 EP disclosed
WO-1988009350-A1 IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD CREST-FOAM COPORATION (US) 1988-12-01 WO disclosed
US-4469864-A MAIN ABSORPTION NEAR 600 TO 700 NANOMETERS FUJI PHOTO FILM CO., LTD. (JP) 1984-09-04 US disclosed
US-4389474-A Thiopyrylium compounds and photoconductive compositions containing said compounds FUJI PHOTO FILM CO., LTD. (JP) 1983-06-21 US disclosed
US-3999989-A SALTS OF INDOLINE SPIROBENZOPYRANS FUJI PHOTO FILM CO., LTD. (JA) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010624-A1 TRICYCLIC COMPOUNDS AND RELATED COMPOSITIONS, ZINC ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS SOD1, SOD3, SLC39A11 NOX1 272/4885MAPT 1714/4885GAA 2759/4885
US-20050154042-A1 N-alkyl pyrroles as HMG-CoA reductase inhibitors HMGCR, DHCR7, CYP11A1 NOX1 2531/4885MAPT 2939/4885GAA 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.