Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | CYBB | P04839 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195556 | 0.79 | NOX1 (0.44) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL8749550 | 0.77 | NOX1 (0.53) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL8966024 | 0.77 | NOX1 (0.46) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL14988086 | 0.76 | NOX1 (0.42) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL9104070 | 0.76 | GAA (0.41) | NOX1GAAMAPTMEN1KMT2A | |
| Iodide SCHEMBL13386087 | 0.75 | NOX1 (0.50) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL31657639 | 0.75 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL1719765 | 0.75 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL1078779 | 0.74 | NOX1 (0.46) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL28909424 | 0.74 | NOX1 (0.53) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | Bioimics AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222466-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2017-12-28 | — | — | WO | disclosed |