Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.78 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.59 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11761270 | 0.89 | AKR1C3 (0.93) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL11037919 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL29481380 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL11262826 | 0.88 | AKR1C3 (0.78) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL11255524 | 0.86 | AKR1C3 (0.74) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL11267918 | 0.84 | AKR1C3 (0.72) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL5268342 | 0.84 | AKR1C3 (0.78) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL11615785 | 0.81 | AKR1C3 (0.73) | AKR1C3AKR1C2PTGS1PTGS2GLO1 | |
| SCHEMBL11086794 | 0.81 | AKR1C3 (0.76) | AKR1C3AKR1C2PTGS1PTGS2TUBB1 | |
| SCHEMBL10874423 | 0.80 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS1PTGS2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084127-B1 | PROCESS FOR PREPARING ACEMATICINE | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1986-04-02 | — | — | EP | claimed |
| CN-100336501-C | Sustained-release round granule composition for treating enteritis and pain and preparation method thereof | JIANQIAO XINYUAN MEDICINE BIOL (CN) | 2007-09-12 | — | — | CN | disclosed |
| CN-1579369-A | Sustained-release round granule composition for treating enteritis and pain and preparation method thereof | JIANQIAO XINYUAN MEDICINE BIOL (CN) | 2005-02-16 | — | — | CN | disclosed |
| EP-0126942-B1 | PREPARATION PROCESS OF ACEMETACIN | Troponwerke GmbH & Co. KG (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4614741-A | INJECTABLE SUSPENSIONS | TROPONWERKE GMBH & CO., KG (DE) | 1986-09-30 | — | — | US | disclosed |
| US-4603210-A | Preparation process of acemetacin | TROPONWERKE GMBH & CO. KG. (DE) | 1986-07-29 | — | — | US | disclosed |
| US-3966956-A | [1-(P-Chlorobenzoyl)-5-methoxy-2-methyl-3-indole]acetoxyacetic acid and salts in treating inflammation | TROPONWERKE DINKLAGE & COMPANY (DT) | 1976-06-29 | — | — | US | disclosed |