Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 1.00 |
| ▸ | AKR1C2 | P52895 | 5/20 | 1.00 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.57 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037919 | 1.00 | AKR1C3 (1.00) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| Acetic Acid SCHEMBL11761270 | 0.96 | AKR1C3 (0.93) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL16746715 | 0.89 | AKR1C3 (0.81) | AKR1C3AKR1C2TUBB1PTGS1KDM4E | |
| SCHEMBL29596462 | 0.89 | AKR1C3 (0.80) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL5268342 | 0.88 | AKR1C3 (0.78) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL10788768 | 0.88 | AKR1C3 (0.78) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL11262826 | 0.88 | AKR1C3 (0.78) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL11086794 | 0.87 | AKR1C3 (0.76) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL29941900 | 0.87 | AKR1C3 (0.77) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 | |
| SCHEMBL15684644 | 0.87 | AKR1C3 (0.77) | AKR1C3AKR1C2TUBB1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157952-A1 | METHOD FOR IMPROVING THE STABILITY OF A PHARMACEUTICAL COMPOSITION COMPRISING A HIGH PENETRATION DRUG, AND THE PHARMACEUTICAL COMPOSITION OBTAINED THEREFROM | TECHFIELDS INC. (US) | 2023-05-25 | — | — | US | claimed |
| EP-4121113-A1 | METHOD FOR IMPROVING THE STABILITY OF A PHARMACEUTICAL COMPOSITION COMPRISING A HIGH PENETRATION DRUG, AND THE PHARMACEUTICAL COMPOSITION OBTAINED THEREFROM | TECHFIELDS INC. (US) | 2023-01-25 | — | — | EP | claimed |
| CN-115484984-A | Method for improving stability of pharmaceutical composition comprising high penetration drug and pharmaceutical composition obtained thereby | 于崇曦 | 2022-12-16 | — | — | CN | claimed |
| CN-111808011-B | High penetration composition and its application | 泰飞尔生物医药(苏州)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-4245752-A2 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | Techfields Inc (US) | 2023-09-20 | — | — | EP | disclosed |
| US-20230270763-A1 | METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES | PASCAL BIOSCIENCES INC (CA) | 2023-08-31 | — | — | US | disclosed |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | TECHFIELDS PHARMA CO., LTD (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230157952-A1 | METHOD FOR IMPROVING THE STABILITY OF A PHARMACEUTICAL COMPOSITION COMPRISING A HIGH PENETRATION DRUG, AND THE PHARMACEUTICAL COMPOSITION OBTAINED THEREFROM | TECHFIELDS INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4121113-A1 | METHOD FOR IMPROVING THE STABILITY OF A PHARMACEUTICAL COMPOSITION COMPRISING A HIGH PENETRATION DRUG, AND THE PHARMACEUTICAL COMPOSITION OBTAINED THEREFROM | TECHFIELDS INC. (US) | 2023-01-25 | — | — | EP | disclosed |
| US-11541029-B2 | High penetration compositions and their applications | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| CN-115484984-A | Method for improving stability of pharmaceutical composition comprising high penetration drug and pharmaceutical composition obtained thereby | 于崇曦 | 2022-12-16 | — | — | CN | disclosed |
| US-20220378705-A1 | METHOD FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING AMPHIPHILIC ACTIVE INGREDIENTS | PHARMADEV SA (CH) | 2022-12-01 | — | — | US | disclosed |
| EP-2170826-B1 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | TECHFIELDS INC (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-112028814-B | Method for preparing amine compound based on novel catalytic Curtius rearrangement reaction | 南京大学 | 2022-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270763-A1 | METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES | CNR1, CNR2, SARS1 | AKR1C3 4258/4885AKR1C2 4474/4885TUBB1 1642/4885 |
| US-20230157952-A1 | METHOD FOR IMPROVING THE STABILITY OF A PHARMACEUTICAL COMPOSITION COMPRISING A HIGH PENETRATION DRUG, AND THE PHARMACEUTICAL COMPOSITION OBTAINED THEREFROM | SLC7A1, ABCG2, SLCO4C1 | AKR1C3 3743/4885AKR1C2 2862/4885TUBB1 2132/4885 |
| US-11541029-B2 | High penetration compositions and their applications | SLC19A1, HIRA, SLC43A1 | AKR1C3 3104/4885AKR1C2 2965/4885TUBB1 732/4885 |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC5A7, SLC19A1, SLC43A1 | AKR1C3 3287/4885AKR1C2 3322/4885TUBB1 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.