Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668615 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2HSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL10936307 | 0.75 | TSHR (0.53) | NPSR1HSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL9921285 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6163277 | 0.70 | NPC1 (0.52) | SMN1; SMN2HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL7697402 | 0.70 | HTT (0.58) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6999270 | 0.70 | PBRM1 (0.58) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL31035124 | 0.69 | KDM4E (0.66) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL294944 | 0.69 | KDM4E (0.66) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6159659 | 0.69 | KDM4E (0.62) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13168478 | 0.68 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694187-A | 5-amino-1-benzamido tetrazole and metal complex thereof | UNIV SICHUAN | 2014-04-02 | — | — | CN | disclosed |
| CN-103694187-A | 5-amino-1-benzamido tetrazole and metal complex thereof | UNIV SICHUAN | 2014-04-02 | — | — | CN | disclosed |
| CN-103694187-A | 5-amino-1-benzamido tetrazole and metal complex thereof | UNIV SICHUAN | 2014-04-02 | — | — | CN | disclosed |
| EP-0135032-B1 | CARBAMATES AND OXALYL AMIDES OF AMINO-N-(1H-TETRAZOL-5-YL) BENZAMIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4526979-A | Carbamates and oxalamides of amino-N-(1H-tetrazol-5-yl)benzamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0135032-A1 | Carbamates and oxalyl amides of amino-N-(1H-tetrazol-5-yl) benzamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-03-27 | — | — | EP | disclosed |