Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936307 | 0.83 | TSHR (0.53) | KMT2ARAB9AMEN1KDM4EALDH1A1 | |
| SCHEMBL10788877 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6163277 | 0.77 | NPC1 (0.52) | SMN1; SMN2KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL12841358 | 0.74 | TSHR (0.70) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL458013 | 0.73 | CYP3A4 (0.51) | SMN1; SMN2KMT2ARAB9AMEN1POLB | |
| SCHEMBL6663174 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9713098 | 0.71 | CYP3A4 (0.49) | KMT2ARAB9AMEN1MAPTCYP3A4 | |
| SCHEMBL918756 | 0.69 | NOTUM (0.47) | SMN1; SMN2KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL27519269 | 0.69 | HSD11B1 (0.54) | RAB9AALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL1118125 | 0.68 | NOTUM (0.45) | SMN1; SMN2KMT2ARAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520414-B | Substituted N- (-1, 3, 4-oxadiazol-2-yl) aryl carboxamides and their use as herbicides | 拜耳作物科学股份公司 | 2023-11-28 | — | — | CN | disclosed |
| US-11304418-B2 | Substituted n-(-1,3,4-oxadiazole-2-yl)aryl carboxamides and the use thereof as herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2022-04-19 | — | — | US | disclosed |
| US-20210076680-A1 | SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-03-18 | — | — | US | disclosed |
| EP-3601242-A1 | SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018177871-A1 | SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | WO | disclosed |
| EP-2152677-A1 | ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-02-17 | — | — | EP | disclosed |
| EP-2148868-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008138917-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008135447-A1 | ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-11-13 | — | — | WO | disclosed |
| CN-1143856-C | Novel substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) [1,4] diazepan-1-yl)-1-(aryl) butyl) benzamides useful for treatment of allergic diseases | ���µ�˹ҩ�﹫˾ | 2004-03-31 | — | — | CN | disclosed |
| CN-1136191-C | Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists | ������ҩ������˾ | 2004-01-28 | — | — | CN | disclosed |
| CN-1115341-C | Novel substituted N-methyl-N- (4- (4- (1H-benzimidazol-2-ylamino) piperidin-1-yl) -2- (aryl) butyl) benzamides for the treatment of allergic diseases | AVENTIS PHARMACEUTICALS CORP (US) | 2003-07-23 | — | — | CN | disclosed |
| CN-1096460-C | Novel substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl) butyl) benzamides useful for treatment of allergic diseases | AVENTIS PHARMA INC (US) | 2002-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11304418-B2 | Substituted n-(-1,3,4-oxadiazole-2-yl)aryl carboxamides and the use thereof as herbicides | DDT, NAT1, AADAC | SMN1; SMN2 1878/4885KMT2A 771/4885RAB9A 4414/4885 |
| US-20210076680-A1 | SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES | DDT, NAT1, AADAC | SMN1; SMN2 1878/4885KMT2A 771/4885RAB9A 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.