SCHEMBL9921285

SCHEMBL9921285

Nc1cccc(C(=O)NNC(=O)c2cccc(N)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HSD17B10 Q99714 1/20 0.59
PBRM1 Q86U86 1/20 0.59
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
KDM4C Q9H3R0 1/20 0.57
KAT6A Q92794 1/20 0.55
PTGS1 P23219 2/20 0.54
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
NPC1 O15118 2/20 0.50
HDAC1 Q13547 1/20 0.50
F2 P00734 1/20 0.50
PLG P00747 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
MITF O75030 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27542687 0.94 SMN1; SMN2 (0.54) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL7867966 0.91 ALDH1A1 (0.54) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL6159659 0.85 KDM4E (0.62) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL294944 0.85 KDM4E (0.66) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL31035124 0.85 KDM4E (0.66) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL29944867 0.83 HDAC8 (0.63) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL13168478 0.83 SMN1; SMN2 (0.56) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL21424259 0.83 SMN1; SMN2 (0.56) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL520073 0.83 HDAC8 (0.63) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E
SCHEMBL3673984 0.82 SMN1; SMN2 (0.56) SMN1; SMN2NPSR1HSD17B10PBRM1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9169339-B2 Curable composition, molded product and method for producing molded product DAIKIN INDUSTRIES, LTD. (JP) 2015-10-27 US disclosed
US-9169339-B2 Curable composition, molded product and method for producing molded product DAIKIN INDUSTRIES, LTD. (JP) 2015-10-27 US disclosed
US-20130190456-A1 CURABLE COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2013-07-25 US disclosed
US-20130190456-A1 CURABLE COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2013-07-25 US disclosed
WO-2012077583-A1 CURABLE COMPOSITION, MOLDED PRODUCT AND METHOD FOR PRODUCING MOLDED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2012-06-14 WO disclosed