SCHEMBL10789643

SCHEMBL10789643

O=C(O)c1n[nH]cc1S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3948762 0.82 CA2 (0.38) ALDH1A1HSD17B10KDM4ELMNA
Hydrochloric Acid SCHEMBL3955087 0.81 CA2 (0.37) ALDH1A1HSD17B10TDP1KDM4ELMNA
SCHEMBL5224094 0.77 NPSR1 (0.45) ALDH1A1KDM4ELMNA
SCHEMBL16209016 0.72 KDM4E (0.36) ALDH1A1HSD17B10KDM4ELMNAHCAR2
SCHEMBL17782009 0.71 TTR (0.34) ALDH1A1CASP1CASP7HSD17B10TDP1
SCHEMBL353093 0.70
SCHEMBL950861 0.68
SCHEMBL649146 0.68
SCHEMBL1020837 0.68
SCHEMBL950773 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4677199-A Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals BASF AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed