Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363360 | 0.77 | CYP2D6 (0.56) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL30234234 | 0.77 | ADRB2 (0.59) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL11066158 | 0.77 | ADRB3 (0.58) | ADRB2ADRB1ADRB3KMT2ALMNA | |
| SCHEMBL11078899 | 0.76 | MEN1 (0.70) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL22639907 | 0.74 | CYP2D6 (0.74) | ADRB2ADRB1ADRB3CYP2D6HTT | |
| SCHEMBL22640159 | 0.74 | CYP2D6 (0.74) | ADRB2ADRB1ADRB3CYP2D6HTT | |
| SCHEMBL11719416 | 0.74 | CYP2D6 (0.52) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL10786534 | 0.74 | CYP2D6 (0.58) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL10364314 | 0.74 | CYP2D6 (0.58) | ADRB2ADRB1ADRB3CYP2D6ITGB3 | |
| SCHEMBL10363672 | 0.74 | CYP2D6 (0.61) | ADRB2ADRB1ADRB3CYP2D6ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665094-A | GLAUCOMA | MERCK & CO., INC. (US) | 1987-05-12 | — | — | US | claimed |