Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075167 | 0.85 | ADRB2 (0.76) | ADRB3ADRB2ADRB1LMNATDP1 | |
| SCHEMBL11078899 | 0.83 | MEN1 (0.70) | ADRB3ADRB2ADRB1LMNATDP1 | |
| SCHEMBL9630745 | 0.78 | ADRB2 (0.77) | ADRB3ADRB2ADRB1LMNATDP1 | |
| SCHEMBL6016784 | 0.78 | ADRB2 (0.77) | ADRB3ADRB2ADRB1LMNATDP1 | |
| SCHEMBL10868115 | 0.78 | ALDH1A1 (0.53) | ADRB3ADRB2ADRB1LMNAKMT2A | |
| SCHEMBL924496 | 0.78 | KMT2A (0.63) | TDP1GLACYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL10840777 | 0.77 | ADRB2 (0.75) | ADRB3ADRB2ADRB1LMNATDP1 | |
| SCHEMBL10789653 | 0.77 | ADRB2 (0.61) | ADRB3ADRB2ADRB1LMNATDP1 | |
| SCHEMBL11078398 | 0.77 | ADRB3 (0.75) | ADRB3ADRB2ADRB1LMNACYP1A2 | |
| SCHEMBL10936166 | 0.77 | ADRB3 (0.62) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450115-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AND CARDIOTONIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| US-4450115-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AND CARDIOTONIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| US-4381398-A | Amino-alcohol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-04-26 | — | — | US | disclosed |