Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790964 | 0.88 | FLT3 (0.46) | KDM4EGAATSHRFLT3ELANE | |
| SCHEMBL10786490 | 0.87 | GAA (0.52) | KDM4EGAATSHRFLT3ALDH1A1 | |
| SCHEMBL10445306 | 0.85 | KDM4E (0.55) | KDM4ETSHRELANEALDH1A1TP53 | |
| SCHEMBL6931907 | 0.84 | GAA (0.41) | KDM4EGAATSHRFLT3ELANE | |
| Hydrochloric Acid SCHEMBL5582116 | 0.84 | KDM4E (0.54) | KDM4ETSHRELANEALDH1A1TP53 | |
| SCHEMBL8638210 | 0.83 | GAA (0.57) | KDM4EGAATSHRFLT3ALDH1A1 | |
| SCHEMBL8440044 | 0.82 | KDM4E (0.77) | KDM4EGAATSHRELANEALDH1A1 | |
| SCHEMBL2902590 | 0.82 | FLT3 (0.66) | KDM4EGAATSHRFLT3ALDH1A1 | |
| SCHEMBL7705110 | 0.82 | GAA (0.41) | KDM4EGAATSHRFLT3ELANE | |
| SCHEMBL4533571 | 0.80 | ELANE (0.51) | GAAELANEALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661576-A | LIQUID CRYSTALS | THOMSON-CSF (FR) | 1987-04-28 | — | — | US | disclosed |