SCHEMBL6931907

SCHEMBL6931907

C=CCOc1ccc(-c2cc(OC(=O)C(=C)C)ccc2C(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.41
TSHR P16473 1/20 0.41
MGAM O43451 3/20 0.39
SI P14410 3/20 0.39
MGAM2 Q2M2H8 3/20 0.39
ELANE P08246 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
FFAR1 O14842 1/20 0.38
POLB P06746 3/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 2/20 0.37
PKM P14618 1/20 0.36
ALDH2 P05091 1/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7705110 0.95 GAA (0.41) GAATSHRMGAMSIMGAM2
SCHEMBL10790899 0.84 KDM4E (0.51) GAATSHRELANEMAPTKMT2A
SCHEMBL1945679 0.82 ELANE (0.52) GAATSHRELANESMN1; SMN2MAPT
SCHEMBL9446930 0.82 SMN1; SMN2 (0.54) GAATSHRMGAMSIMGAM2
SCHEMBL9446915 0.81 GAA (0.43) GAATSHRMGAMSIMGAM2
SCHEMBL4533571 0.81 ELANE (0.51) GAAELANESMN1; SMN2MAPTMEN1
SCHEMBL5095993 0.80 GAA (0.47) GAATSHRSMN1; SMN2MAPTMEN1
SCHEMBL9446935 0.80 GAA (0.48) GAATSHRMGAMSIMGAM2
SCHEMBL9127370 0.80 ALDH2 (0.54) GAATSHRMGAMSIMGAM2
SCHEMBL8962717 0.80 RARB (0.53) TSHRSMN1; SMN2FFAR1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0892023-B1 Opaque pigment flakes CIBA SC HOLDING AG (CH) 2003-12-03 EP disclosed
EP-0892023-A1 Opaque pigment flakes Ciba SC Holding AG (CH) 1999-01-20 EP disclosed
US-5211877-A Crosslinked resins CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-05-18 US disclosed