SCHEMBL4533571

SCHEMBL4533571

C=CCOc1ccc(OC(=O)C(=C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.51
KMT2A Q03164 3/20 0.48
ATM Q13315 1/20 0.48
NPC1 O15118 4/20 0.47
RAB9A P51151 3/20 0.47
MAPT P10636 3/20 0.47
POLB P06746 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TP53 P04637 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
HTT P42858 2/20 0.42
APEX1 P27695 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2D6 P10635 1/20 0.42
CHRNB2 P17787 3/20 0.42
CHRNB4 P30926 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6931905 0.91 ELANE (0.51) ELANEKMT2AATMNPC1RAB9A
SCHEMBL7259849 0.91 ELANE (0.51) ELANEKMT2AATMNPC1RAB9A
SCHEMBL8026565 0.88 NPC1 (0.56) ELANEKMT2ANPC1RAB9AMAPT
SCHEMBL8026563 0.88 NPC1 (0.56) ELANEKMT2ANPC1RAB9AMAPT
SCHEMBL8023960 0.87 KMT2A (0.48) ELANEKMT2AATMNPC1RAB9A
SCHEMBL7924946 0.84 GAA (0.45) ELANEKMT2ANPC1RAB9AMAPT
SCHEMBL5049713 0.84 LMNA (0.52) ELANEKMT2ANPC1RAB9AMAPT
SCHEMBL17091467 0.83 ELANE (0.48) ELANEKMT2AATMNPC1RAB9A
SCHEMBL8024346 0.82 KMT2A (0.45) ELANEKMT2ANPC1RAB9AMAPT
SCHEMBL56436 0.82 ELANE (0.69) ELANEKMT2AATMRAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US claimed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO claimed
US-7569328-B2 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION (JP) 2009-08-04 US disclosed
US-20080044763-A1 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION 2008-02-21 US disclosed
US-20040234893-A9 Resin composition and thermo/photosensitive composition FUJI PHOTO FILM CO., LTD. 2004-11-25 US disclosed
US-20040131972-A1 Resin composition and thermo/photosensitive composition FUJI PHOTO FILM CO., LTD. 2004-07-08 US disclosed
EP-1389521-A2 Thermosensitive/photosensitive resin composition Fuji Photo Film Co., Ltd. (JP) 2004-02-18 EP disclosed
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US disclosed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO disclosed