Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 4/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31317414 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL37898 | 0.93 | CA12 (0.39) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL4924551 | 0.91 | CA12 (0.39) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL819799 | 0.87 | CA12 (0.41) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL28532792 | 0.86 | TSHR (0.43) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL4918826 | 0.86 | CA12 (0.41) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL28050404 | 0.85 | CA12 (0.38) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL16028223 | 0.84 | CA12 (0.38) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL6698542 | 0.84 | CA12 (0.39) | ALDH1A1TSHRCA12CA6CA7 | |
| SCHEMBL14483169 | 0.83 | DNM1 (0.48) | ALDH1A1TSHRCA9CA2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699988-A | Novel aminofunctional silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| US-4618689-A | Novel aminofunctional silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1986-10-21 | — | — | US | disclosed |