Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 1.00 |
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.60 |
| ▸ | PDE2A | O00408 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CCR4 | P51679 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675224 | 1.00 | HSD17B3 (1.00) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| Phosphoric Acid SCHEMBL27762580 | 0.94 | HSD17B3 (0.88) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL10792491 | 0.87 | HSD17B3 (0.77) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL10791381 | 0.87 | HSD17B3 (0.77) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL31366988 | 0.86 | HSD17B3 (1.00) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL591899 | 0.86 | HSD17B3 (1.00) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL28446883 | 0.84 | HSD17B3 (0.96) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL609585 | 0.84 | HSD17B3 (0.73) | HSD17B3ESR1ESR2PDE2AKDM4E | |
| SCHEMBL6907581 | 0.80 | HSD17B3 (0.75) | HSD17B3ESR1ESR2ERAP1PDE2A | |
| SCHEMBL1024770 | 0.80 | HSD17B3 (1.00) | HSD17B3ESR1ESR2ERAP1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1612939-A | Method for highly sensitive and continuous detection of Protein Tyrosine Phosphatase (PTP) using 6, 8-difluoro-4-methyl-7-hydroxycoumarin phosphate | AVENTIS PHARMA GMBH (DE) | 2005-05-04 | — | — | CN | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | disclosed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | disclosed |
| CN-112961205-B | Preparation method and medical application of sulfonamide compounds with coumarin and glycosyl structures | 沈阳药科大学 | 2022-10-14 | — | — | CN | disclosed |
| EP-4036085-A1 | COMPOUNDS FOR OPTICALLY ACTIVE OPHTHALMIC DEVICES | AMO Ireland (IE) | 2022-08-03 | — | — | EP | disclosed |
| CN-112961205-A | Preparation method and medical application of sulfonamide compounds with coumarin and glycosyl structures | 沈阳药科大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-105566269-A | Preparation and pharmacological effects of coumarin derivative and application of coumarin derivative to treatment on pruritus | UNIV BEIJING | 2016-05-11 | — | — | CN | disclosed |
| CN-105524034-A | Preparation method of coumarin derivative, pharmacological effect of coumarin derivative and use of coumarin derivative in treatment on cerebral ischemia | UNIV BEIJING | 2016-04-27 | — | — | CN | disclosed |
| CN-102459303-A | Phytases, nucleic acids encoding them and methods of making and using them | VERENIUM CORP | 2012-05-16 | — | — | CN | disclosed |
| CN-102317296-A | Fused aromatic PTP-1B inhibitors | MERCK FROSST CANADA LTD | 2012-01-11 | — | — | CN | disclosed |
| CN-102137936-A | Particles for detecting intracellular targets | UNIV NORTHWESTERN | 2011-07-27 | — | — | CN | disclosed |
| CN-102076847-A | Rna polyphosphatase compositions, kits, and uses thereof | EPICT TECHNOLOGIES CORP | 2011-05-25 | — | — | CN | disclosed |
| CN-102076851-A | Selective 5' ligation tagging of rna | EPICT TECHNOLOGIES CORP | 2011-05-25 | — | — | CN | disclosed |
| CN-101282719-A | Glepp-1 inhibitors for the treatment of autoimmune and/or inflammatory diseases | SERONO LAB (CH) | 2008-10-08 | — | — | CN | disclosed |
| CN-1665790-A | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES INC (US) | 2005-09-07 | — | — | CN | disclosed |
| CN-1612939-A | Method for highly sensitive and continuous detection of Protein Tyrosine Phosphatase (PTP) using 6, 8-difluoro-4-methyl-7-hydroxycoumarin phosphate | AVENTIS PHARMA GMBH (DE) | 2005-05-04 | — | — | CN | disclosed |
| EP-0111746-B1 | SULFONIC-ACID ESTERS OF HYDROXYCOUMARINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4618622-A | ANTIDEPRESSANTS, ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | HSD17B3 3080/4885ESR1 3856/4885ESR2 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.