Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792269 | 0.86 | GPR84 (0.38) | SMN1; SMN2EGFRP2RX7ALDH1A1TAAR1 | |
| SCHEMBL10792280 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2ARALDH1A1HTR2CHTR2B | |
| SCHEMBL10795503 | 0.80 | TAAR1 (0.46) | ARALDH1A1TAAR1USP2GPR84 | |
| SCHEMBL10790886 | 0.79 | GAA (0.49) | ALDH1A1HPGDTAAR1 | |
| SCHEMBL6247431 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL82538 | 0.78 | TAAR1 (0.43) | SMN1; SMN2ALDH1A1HPGDTAAR1 | |
| SCHEMBL9219681 | 0.77 | GPR84 (0.61) | ALDH1A1HTR6GPR84 | |
| Water SCHEMBL10981448 | 0.76 | TAAR1 (0.42) | SMN1; SMN2ALDH1A1HPGDTAAR1 | |
| Fluoride SCHEMBL28059937 | 0.75 | TAAR1 (0.41) | SMN1; SMN2ALDH1A1HPGDTAAR1 | |
| SCHEMBL10792457 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2P2RX7ALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |