Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | AHR | P35869 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559876 | 0.81 | GPR84 (0.61) | GPR84MEN1KMT2AAHRCYP3A4 | |
| SCHEMBL2794875 | 0.78 | GPR84 (0.56) | GPR84MEN1KMT2AAHRCYP3A4 | |
| Arundine SCHEMBL325162 | 0.77 | MEN1 (1.00) | GPR84MEN1KMT2AAHRCYP3A4 | |
| SCHEMBL16431196 | 0.77 | GPR84 (0.69) | GPR84MEN1KMT2AAHRCYP3A4 | |
| SCHEMBL10792018 | 0.77 | SMN1; SMN2 (0.41) | GPR84ALDH1A1HTR6 | |
| SCHEMBL20204745 | 0.76 | GPR84 (0.57) | GPR84MEN1KMT2AAHRCYP3A4 | |
| Arundine SCHEMBL28335217 | 0.75 | MEN1 (0.95) | GPR84MEN1KMT2AAHRCYP3A4 | |
| SCHEMBL735576 | 0.74 | GPR84 (0.65) | GPR84MEN1KMT2AAHRCYP3A4 | |
| SCHEMBL10792280 | 0.74 | SMN1; SMN2 (0.49) | KMT2AMAPTALDH1A1KDM4EHTR6 | |
| SCHEMBL31744758 | 0.74 | GPR84 (0.65) | GPR84MEN1KMT2AAHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446010-B1 | Imidazole derivatives and antiepileptics comprising said imidazole derivatives as effective ingredients | MITSUI TOATSU CHEMICALS (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5112841-A | Anticonvulsants | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0446010-A1 | Imidazole derivatives and antiepileptics comprising said imidazole derivatives as effective ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-09-11 | — | — | EP | disclosed |