Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.75 |
| ▸ | PGR | P06401 | 4/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | DRD2 | P14416 | 1/20 | 0.75 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.75 |
| ▸ | CNR1 | P21554 | 1/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.75 |
| ▸ | MMP1 | P03956 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | AR | P10275 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 3/20 | 0.67 |
| ▸ | MLNR | O43193 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betamethasone Acibutate SCHEMBL11143598 | 1.00 | NR3C1 (0.75) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Acibutate SCHEMBL29438080 | 1.00 | NR3C1 (0.75) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Acibutate SCHEMBL11143594 | 1.00 | NR3C1 (0.75) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Acibutate SCHEMBL10792705 | 1.00 | NR3C1 (0.75) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Acibutate SCHEMBL10792708 | 1.00 | NR3C1 (0.75) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL11430075 | 0.92 | NR3C1 (0.75) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL11882871 | 0.91 | NR3C1 (0.81) | NR3C1PGRCYP3A4MMP1USP2 | |
| SCHEMBL10792533 | 0.91 | NR3C1 (0.81) | NR3C1PGRCYP3A4MMP1USP2 | |
| SCHEMBL11882866 | 0.91 | NR3C1 (0.81) | NR3C1PGRCYP3A4MMP1USP2 | |
| SCHEMBL25370010 | 0.91 | NR3C1 (0.91) | NR3C1PGRNR1I2MAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4655971-A | USING AN ANHYDRIDE AND ACID CATALYST TO ESTERIFY HYDROXY'S IN THE 17- OR 17- AND 21-POSITION; ENHANCED ANTIINFLAMMATORY AGENTS | PLURICHEMIE ANSTALT (LI) | 1987-04-07 | — | — | US | disclosed |