Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.91 |
| ▸ | PGR | P06401 | 5/20 | 0.91 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.91 |
| ▸ | MAPT | P10636 | 2/20 | 0.91 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.91 |
| ▸ | DRD2 | P14416 | 1/20 | 0.91 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.81 |
| ▸ | USP2 | O75604 | 5/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | MLNR | O43193 | 1/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.81 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.81 |
| ▸ | PPARG | P37231 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.75 |
| ▸ | CNR1 | P21554 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30491082 | 1.00 | NR3C1 (0.91) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL8077638 | 1.00 | NR3C1 (0.91) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL13028946 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL11429865 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL4566 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL20097870 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL10013893 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL9768468 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Dexamethasone Dipropionate SCHEMBL43107 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL14339597 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230277452-A1 | COMPOSITIONS, DEVICES AND METHODS FOR TREATING NASAL, OTIC AND OTHER TISSUE INFECTION AND/OR INFLAMMATION | OTICARA, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| CN-116600785-A | Compositions, devices and methods for treating infection and/or inflammation of the nose, ear and other tissues | 奥蒂卡拉股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-4203958-A1 | COMPOSITIONS DEVICES AND METHODS FOR TREATING NASAL, OTIC AND OTHER TISSUE INFECTION AND/OR INFLAMMATION | Oticara, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022047042-A1 | COMPOSITIONS DEVICES AND METHODS FOR TREATING NASAL, OTIC AND OTHER TISSUE INFECTION AND/OR INFLAMMATION | OTICARA, INC. (US) | 2022-03-03 | — | — | WO | disclosed |