Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794761 | 0.85 | SLC18A2 (0.39) | SLC18A2PKMKLK7TSHRMAOA | |
| SCHEMBL10794702 | 0.85 | SLC18A2 (0.39) | SLC18A2PKMKLK7TSHRMAOA | |
| SCHEMBL10794322 | 0.82 | SLC18A2 (0.41) | SLC18A2PKMKLK7 | |
| SCHEMBL10793076 | 0.81 | DRD1 (0.33) | SLC18A2 | |
| SCHEMBL9832217 | 0.79 | CYP3A4 (0.52) | TSHR | |
| SCHEMBL10796024 | 0.79 | MEN1 (0.44) | SLC18A2 | |
| SCHEMBL9832224 | 0.78 | SMPD1 (0.43) | — | |
| SCHEMBL9827555 | 0.78 | CYP3A4 (0.50) | TSHR | |
| SCHEMBL9827558 | 0.78 | SMPD1 (0.43) | — | |
| SCHEMBL9829660 | 0.77 | CYP3A4 (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4680310-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1987-07-14 | — | — | US | disclosed |