Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603957 | 0.93 | EGFR (0.53) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10604706 | 0.92 | EGFR (0.57) | EGFRTSHRHPGDNPC1RAB9A | |
| SCHEMBL10603961 | 0.84 | EGFR (0.46) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10601747 | 0.84 | EGFR (0.65) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21480766 | 0.84 | HPGD (0.57) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8559873 | 0.81 | EGFR (0.48) | EGFRHPGDSRCALDH1A1MAPT | |
| SCHEMBL9696028 | 0.81 | EGFR (0.42) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9696955 | 0.79 | MAPT (0.44) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10601087 | 0.79 | TSHR (0.39) | EGFRTSHRSRCHDAC1BRD4 | |
| SCHEMBL10601752 | 0.78 | EGFR (0.54) | EGFRHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673671-A | CONVERSION TO MONO O-PHOSPHATE ESTER | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |