Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696962 | 0.92 | RAB9A (0.44) | MAPTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL9695986 | 0.88 | MAPT (0.43) | MAPTHPGDALDH1A1LMNAEGFR | |
| SCHEMBL9696041 | 0.86 | MAPT (0.41) | MAPTHPGDALDH1A1LMNAEGFR | |
| SCHEMBL9696537 | 0.86 | MAPT (0.41) | MAPTHPGDALDH1A1LMNAEGFR | |
| SCHEMBL9696028 | 0.85 | EGFR (0.42) | MAPTHPGDALDH1A1LMNAEGFR | |
| SCHEMBL10603957 | 0.85 | EGFR (0.53) | MAPTHPGDALDH1A1LMNAEGFR | |
| SCHEMBL8559873 | 0.82 | EGFR (0.48) | MAPTHPGDALDH1A1LMNAEGFR | |
| SCHEMBL9696940 | 0.80 | MAPT (0.45) | MAPTALDH1A1LMNAKMT2AESR1 | |
| SCHEMBL9695990 | 0.80 | RAB9A (0.43) | MAPTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL10603961 | 0.79 | EGFR (0.46) | HPGDLMNAEGFRKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |