Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696037 | 0.89 | ALOX15 (0.40) | EGFRALDH1A1NPC1RAB9ACA12 | |
| SCHEMBL10603957 | 0.87 | EGFR (0.53) | EGFRHPGDALDH1A1MAPTSRC | |
| SCHEMBL9696955 | 0.85 | MAPT (0.44) | EGFRHPGDALDH1A1MAPTSRC | |
| SCHEMBL9696975 | 0.85 | ADRB2 (0.41) | EGFRHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL9694877 | 0.84 | HPGD (0.37) | EGFRHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL9696041 | 0.84 | MAPT (0.41) | EGFRHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL9695943 | 0.84 | ELANE (0.47) | EGFRHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL9696537 | 0.84 | MAPT (0.41) | EGFRHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL9696523 | 0.84 | MAPT (0.42) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8559873 | 0.84 | EGFR (0.48) | EGFRHPGDALDH1A1MAPTSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |