SCHEMBL1079328

SCHEMBL1079328

O=C(O)CC1(Br)C2C=CC(C2)C1(Br)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 14/20 0.44
KMT2A Q03164 2/20 0.37
PKM P14618 1/20 0.37
AKR1C1 Q04828 1/20 0.34
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977926 0.63 HSD11B1 (0.69) HSD11B1KMT2AAKR1C1TSHRLMNA
SCHEMBL625584 0.63 HSD11B1 (0.64) HSD11B1KMT2APKMAKR1C1TSHR
SCHEMBL1741105 0.62 MAOB (0.39)
SCHEMBL1361875 0.62 TSHR (0.58) HSD11B1KMT2APKMAKR1C1TSHR
SCHEMBL4880104 0.62 KDM4E (0.35) HSD11B1KMT2AMEN1
SCHEMBL5365797 0.61 HSD11B1 (0.72) HSD11B1KMT2AAKR1C1TSHRLMNA
SCHEMBL7813280 0.61 HSD11B1 (1.00) HSD11B1KMT2AMEN1
SCHEMBL1079211 0.61 HSD11B1 (0.38) HSD11B1KMT2APKMAKR1C1LMNA
SCHEMBL13216921 0.60 HSD11B1 (1.00) HSD11B1KMT2APKMMEN1
Hydrochloric Acid SCHEMBL11526870 0.60 HSD11B1 (0.70) HSD11B1KMT2AAKR1C1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211514-B2 Reverse dispersion retardation film and liquid crystal display device using the same JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-07-03 US disclosed
US-7867581-B2 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2011-01-11 US disclosed
US-20090156770-A1 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2009-06-18 US disclosed
EP-2060937-A1 RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME Nippon Oil Corporation (JP) 2009-05-20 EP disclosed