SCHEMBL1079211

SCHEMBL1079211

O=C(O)CC1C2C=CC(C2)C1(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.38
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.33
EGFR P00533 1/20 0.31
P2RX7 Q99572 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31
PKM P14618 1/20 0.31
AKR1C1 Q04828 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078417 0.82 ALDH1A1 (0.44) HSD11B1ALDH1A1TDP1KMT2AMEN1
SCHEMBL1078394 0.79 KMT2A (0.37) HSD11B1ALDH1A1TDP1KMT2AMEN1
SCHEMBL4248753 0.69 MAOA (0.34) ALDH1A1TDP1LMNAGAASLC6A2
SCHEMBL1077167 0.69 KDM4E (0.34) ALDH1A1TDP1KMT2AMEN1POLB
SCHEMBL1739479 0.69 KDM4E (0.36) HSD11B1ALDH1A1TDP1KMT2AMEN1
SCHEMBL6269153 0.67 ALDH1A1 (0.36) ALDH1A1TDP1KMT2AMEN1POLB
SCHEMBL1733068 0.65 TDP1 (0.33) HSD11B1ALDH1A1TDP1KMT2AMEN1
SCHEMBL1079328 0.61 HSD11B1 (0.44) HSD11B1KMT2AMEN1LMNAPKM
SCHEMBL1076910 0.60 SMN1; SMN2 (0.42) ALDH1A1KMT2AMEN1KDM4ELMNA
SCHEMBL11611684 0.60 KDM4E (0.44) ALDH1A1TDP1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211514-B2 Reverse dispersion retardation film and liquid crystal display device using the same JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-07-03 US disclosed
EP-2390690-A1 INVERSELY DISPERSIVE RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JX Nippon Oil & Energy Corporation (JP) 2011-11-30 EP disclosed
US-7867581-B2 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2011-01-11 US disclosed
US-20090156770-A1 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2009-06-18 US disclosed
EP-2060937-A1 RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME Nippon Oil Corporation (JP) 2009-05-20 EP disclosed