Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 6/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 6/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.35 |
| ▸ | HCK | P08631 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.34 |
| ▸ | CSK | P41240 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159982 | 0.70 | SCN4A (0.38) | SRCABL1HCKEGFRKCNH2 | |
| SCHEMBL19772682 | 0.69 | ADORA2A (0.32) | ADORA2AADORA1 | |
| SCHEMBL12341466 | 0.67 | L3MBTL1 (0.32) | ADORA2AADORA1 | |
| SCHEMBL11967313 | 0.66 | ADORA2A (0.30) | ADORA2AADORA1 | |
| SCHEMBL20159730 | 0.63 | MAP4K4 (0.39) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL9604095 | 0.63 | — | — | |
| SCHEMBL16828155 | 0.60 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL16828146 | 0.59 | CDK1 (0.50) | MEN1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16828217 | 0.59 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL1576984 | 0.57 | MEN1 (0.43) | MEN1CYP1A2KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103537-B1 | N-ARYLSULFONYL-N'-TRIAZOLYL UREA | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |
| EP-0103537-A2 | N-arylsulfonyl-N'-triazolyl urea | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |