Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159730 | 0.83 | MAP4K4 (0.39) | KDM4EALDH1A1MAPTPIK3CDABL1 | |
| SCHEMBL20138803 | 0.82 | SCN4A (0.38) | SCN4AL3MBTL1MEN1KMT2ASCN9A | |
| SCHEMBL20159299 | 0.79 | HTR2A (0.37) | KDM4EALDH1A1MAPTKCNH2PIK3CD | |
| SCHEMBL20159650 | 0.74 | PSEN1 (0.51) | SCN9ASCN5AHTR7ABL1SRC | |
| SCHEMBL10793571 | 0.70 | MPO (0.39) | MEN1KMT2AKCNH2PIK3CDABL1 | |
| SCHEMBL23504771 | 0.67 | HTR2A (0.41) | L3MBTL1SCN9A | |
| SCHEMBL20138669 | 0.67 | HTR2A (0.41) | L3MBTL1SCN9AKCNH2SCN5A | |
| SCHEMBL20142954 | 0.67 | MAP4K4 (0.35) | L3MBTL1ALDH1A1MAPTHTTPIK3CD | |
| SCHEMBL20138683 | 0.67 | — | — | |
| SCHEMBL20142991 | 0.67 | MAPT (0.37) | KDM4EMEN1KMT2ASCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |