SCHEMBL10793752

SCHEMBL10793752

COC(=O)c1ccc(C)c(C)c1OC1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PDE5A O76074 1/20 0.40
KDM4E B2RXH2 5/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PTGER4 P35408 1/20 0.39
KMT2A Q03164 1/20 0.38
CXCR5 P32302 1/20 0.38
PDE4D Q08499 2/20 0.38
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
ATM Q13315 1/20 0.37
YAP1 P46937 1/20 0.37
TSHR P16473 2/20 0.36
RECQL P46063 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28358763 0.99 ALDH1A1 (0.42) ALDH1A1HTTSMN1; SMN2PDE5AKDM4E
SCHEMBL29050940 0.81 CXCR5 (0.53) ALDH1A1PDE5AKDM4EHSD17B10HPGD
SCHEMBL10793746 0.79 ATM (0.45) ALDH1A1HTTSMN1; SMN2HSD17B10KMT2A
SCHEMBL13328396 0.79 CXCR5 (0.57) ALDH1A1HTTPDE5AKDM4EHSD17B10
SCHEMBL12760757 0.78 YAP1 (0.41) ALDH1A1SMN1; SMN2PDE5AKDM4EHSD17B10
SCHEMBL29063013 0.78 ATM (0.44) ALDH1A1HTTSMN1; SMN2HSD17B10NPSR1
SCHEMBL17877001 0.77 CA1 (0.43) ALDH1A1KDM4EHSD17B10HPGDNPSR1
SCHEMBL12794454 0.77 ALDH1A1 (0.43) ALDH1A1HTTSMN1; SMN2KMT2ACXCR5
SCHEMBL12760741 0.75 TSHR (0.50) ALDH1A1HTTSMN1; SMN2PDE5AKDM4E
SCHEMBL730521 0.73 PDE5A (0.48) PDE5AKDM4EKMT2APDE4DPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0168415-B1 UTILIZATION OF SALICYLIC ACID ESTERS AS PERFUMING SUBSTANCES, PERFUMING COMPOSITIONS CONTAINING THEM AND NEW SALICYLIC ACID ESTERS Henkel Kommanditgesellschaft auf Aktien (DE) 1987-08-12 EP claimed