Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798632 | 0.95 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL20597342 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL6360310 | 0.86 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL27816835 | 0.82 | S1PR3 (0.43) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL11151162 | 0.81 | S1PR3 (0.42) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL11780653 | 0.80 | CA2 (0.44) | ALDH1A1HSD17B10CYP2C9CYP2C19CA2 | |
| SCHEMBL3680212 | 0.79 | S1PR3 (0.49) | ALDH1A1CA2S1PR3TYRTSHR | |
| SCHEMBL4620923 | 0.79 | S1PR3 (0.43) | ALDH1A1HSD17B10CA2SMN1; SMN2S1PR3 | |
| SCHEMBL29567634 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CA2SMN1; SMN2S1PR3 | |
| SCHEMBL31513533 | 0.79 | S1PR3 (0.49) | ALDH1A1CA2S1PR3TYRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642240-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |