Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 3/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741668 | 0.84 | ESR1 (0.64) | ESR1ESR2MCHR1LTA4HHTT | |
| SCHEMBL7936761 | 0.83 | ESR1 (0.62) | ABCB1ESR1ESR2MCHR1LTA4H | |
| Hydrochloric Acid SCHEMBL224473 | 0.83 | ESR1 (0.62) | ESR1ESR2MCHR1LTA4HHTT | |
| SCHEMBL6802598 | 0.83 | ESR1 (0.62) | ESR1ESR2MCHR1LTA4H | |
| SCHEMBL7598204 | 0.83 | THRA (0.62) | ABCB1ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL17129733 | 0.82 | L3MBTL1 (0.62) | ABCB1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10885211 | 0.81 | EBP (0.71) | ESR1ESR2MCHR1LTA4HEBP | |
| SCHEMBL9642909 | 0.80 | MAPK1 (0.71) | ABCB1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8172219 | 0.79 | L3MBTL1 (0.74) | ABCB1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10040898 | 0.79 | L3MBTL1 (0.69) | RAB9ASMN1; SMN2MAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4645779-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-02-24 | — | — | US | disclosed |
| EP-0114410-B1 | SUBSTITUTED ALPHA-(ETHYL)-ALPHA-(PHENYL)-(OMEGA-(DIALKYLAMINO)-ALKOXY)-BENZYL ALCOHOLS, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION, AS WELL AS MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-05-14 | — | — | EP | disclosed |