Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790676 | 0.86 | KCNH2 (0.45) | KCNH2RAB9ANPC1TAAR1P2RX7 | |
| SCHEMBL10795646 | 0.86 | SMN1; SMN2 (0.44) | RAB9AP2RX7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10791418 | 0.81 | MEN1 (0.41) | KCNH2RAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL10792243 | 0.75 | P2RX7 (0.43) | RAB9AP2RX7SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6926762 | 0.72 | SMN1; SMN2 (0.47) | RAB9AP2RX7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6929338 | 0.72 | CYP11B1 (0.51) | RAB9AP2RX7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10793121 | 0.71 | KCNH2 (0.40) | KCNH2TAAR1FNTAFNTBHTR7 | |
| SCHEMBL10794794 | 0.71 | AVPR2 (0.41) | P2RX7SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL17493899 | 0.70 | — | — | |
| SCHEMBL10795683 | 0.70 | CYP11B1 (0.49) | RAB9ANPC1P2RX7SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |