SCHEMBL10794895

SCHEMBL10794895

O=C(CCOc1ccccc1)CCOc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
PKM P14618 1/20 0.59
KCNA3 P22001 1/20 0.58
RECQL P46063 2/20 0.58
ALDH1A1 P00352 2/20 0.58
TSHR P16473 1/20 0.58
ALOX15 P16050 1/20 0.56
PARP10 Q53GL7 1/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC2 Q92769 2/20 0.55
MTNR1A P48039 1/20 0.53
MTNR1B P49286 1/20 0.53
MMP3 P08254 1/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
KMT2A Q03164 2/20 0.53
ALOX5 P09917 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361230 0.89 KCNA3 (0.62) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL16787544 0.88 CYP1A2 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL38674 0.86 L3MBTL1 (0.68) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL10877978 0.84 L3MBTL1 (0.66) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL4900016 0.84 CYP1A2 (0.59) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL1308374 0.83 CYP1A2 (0.58) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL6700987 0.83 CYP1A2 (0.58) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL8278956 0.83 MTNR1A (0.59) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL9860498 0.83 CYP1A2 (0.58) CYP1A2CYP3A4CYP2C9CYP2C19PKM
SCHEMBL1328579 0.83 PARP10 (0.61) CYP1A2CYP3A4CYP2C9CYP2C19PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026995-A Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone 国科大杭州高等研究院 2024-05-14 CN claimed
CN-118026995-A Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone 国科大杭州高等研究院 2024-05-14 CN disclosed
CN-112703229-A Enzyme-functionalized coating composition 巴斯夫欧洲公司 2021-04-23 CN disclosed
EP-0133949-B1 WATER DILUTABLE COATING MATERIALS FOR MINERAL AND BITUMINOUS SUBSTRATES, AND METHOD OF MAKING THEM Vianova Kunstharz Aktiengesellschaft (AT) 1987-07-08 EP disclosed
EP-0133949-A1 Water dilutable coating materials for mineral and bituminous substrates, and method of making them Vianova Kunstharz Aktiengesellschaft (AT) 1985-03-13 EP disclosed