Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477127 | 0.97 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL9416938 | 0.97 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL5573089 | 0.94 | ALDH1A1 (0.71) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL10794315 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL10794633 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL9416962 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL5573048 | 0.87 | ALDH1A1 (0.75) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL9314218 | 0.86 | DRD2 (0.51) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL9314523 | 0.86 | DRD2 (0.51) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL9315385 | 0.86 | DRD2 (0.51) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480133-A | Chemical process | ETHYL CORPORATION (US) | 1984-10-30 | — | — | US | claimed |
| US-4456770-A | Chemical process for preparing 1,3 diketones | ETHYL CORPORTATION (US) | 1984-06-26 | — | — | US | claimed |
| US-4456771-A | Chemical process for preparing 1,3-diketones | ETHYL CORPORATION (US) | 1984-06-26 | — | — | US | claimed |
| EP-0163634-A4 | PROCESS FOR PREPARING (3',5'-DIHYDROCARBYL-4'HYDROXYBENZYL)-1,2-DIKETONES. | ETHYL CORP (US) | 1987-08-20 | — | — | EP | disclosed |
| EP-0163634-A1 | PROCESS FOR PREPARING (3',5'-DIHYDROCARBYL-4'HYDROXYBENZYL)-1,2-DIKETONES | ETHYL CORPORATION (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0161252-A1 | PROCESS FOR PREPARING 3,5-DIHYDROCARBYL-4-HYDROXYBENZYLMALONIC ACID ESTERS | ETHYL CORPORATION (US) | 1985-11-21 | — | — | EP | disclosed |
| WO-1985002179-A1 | PROCESS FOR PREPARING (3',5'-DIHYDROCARBYL-4'HYDROXYBENZYL)-1,2-DIKETONES | ETHYL CORPORATION (US) | 1985-05-23 | — | — | WO | disclosed |
| WO-1985002183-A1 | PROCESS FOR PREPARING 3,5-DIHYDROCARBYL-4-HYDROXYBENZYLMALONIC ACID ESTERS | ETHYL CORPORATION (US) | 1985-05-23 | — | — | WO | disclosed |
| US-4480133-A | Chemical process | ETHYL CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4456770-A | Chemical process for preparing 1,3 diketones | ETHYL CORPORTATION (US) | 1984-06-26 | — | — | US | disclosed |
| US-4456771-A | Chemical process for preparing 1,3-diketones | ETHYL CORPORATION (US) | 1984-06-26 | — | — | US | disclosed |
| EP-0105772-A2 | Substituted benzyl diketones and process therefor | ETHYL CORPORATION (US) | 1984-04-18 | — | — | EP | disclosed |
| EP-0103529-A1 | Novel substituted benzylated malonic acid esters and process therefor | ETHYL CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |