Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467474 | 0.92 | CYP1A2 (0.60) | CYP1A2CYP2C9CYP2C19KMT2ACA9 | |
| SCHEMBL9712657 | 0.88 | KMT2A (0.57) | KMT2ACA9CA12CA1CA2 | |
| SCHEMBL11453393 | 0.87 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19KMT2AGAA | |
| SCHEMBL6469761 | 0.87 | ALDH1A1 (0.56) | GAACA9CA12CA1CA2 | |
| SCHEMBL1558023 | 0.83 | KDM4E (0.52) | GAACA9CA12CA1CA2 | |
| SCHEMBL27051701 | 0.82 | KMT2A (0.47) | KMT2ACA9CA12CA1CA2 | |
| SCHEMBL2552794 | 0.82 | KMT2A (0.51) | KMT2ACA9CA12CA1CA2 | |
| SCHEMBL13607858 | 0.82 | CA12 (0.70) | KMT2ACA9CA12CA1CA2 | |
| SCHEMBL4959462 | 0.82 | PTPN1 (0.55) | KMT2ACA9CA12CA1CA2 | |
| SCHEMBL20504730 | 0.81 | PTPN1 (0.54) | KMT2ACA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642240-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |