SCHEMBL2552794

SCHEMBL2552794

CCCOc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.51
ALDH1A1 P00352 2/20 0.51
PTK2B Q14289 1/20 0.51
MEN1 O00255 3/20 0.48
HIF1A Q16665 1/20 0.48
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
PTPN1 P18031 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
FOLH1 Q04609 1/20 0.46
KDM4E B2RXH2 1/20 0.45
RECQL P46063 1/20 0.45
NR1I2 O75469 1/20 0.45
LMNA P02545 1/20 0.45
CHRM2 P08172 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6840729 0.92 KMT2A (0.51) KMT2AALDH1A1PTK2BMEN1CNR1
SCHEMBL8085939 0.90 MEN1 (0.57) KMT2AMEN1PTPN1KDM4ERECQL
SCHEMBL9712657 0.90 KMT2A (0.57) KMT2AALDH1A1PTK2BMEN1HIF1A
SCHEMBL28214715 0.89 LMNA (0.60) KMT2AALDH1A1MEN1CNR1CNR2
SCHEMBL5722029 0.89 LMNA (0.60) KMT2AALDH1A1MEN1CNR1CNR2
SCHEMBL9153749 0.89 LMNA (0.60) KMT2AALDH1A1MEN1CNR1CNR2
SCHEMBL124096 0.86 LMNA (0.55) KMT2AALDH1A1PTK2BMEN1CA12
SCHEMBL29225452 0.85 ALDH1A1 (0.53) KMT2AALDH1A1PTK2BMEN1CA12
SCHEMBL124950 0.84 ALDH1A1 (0.71) KMT2AALDH1A1PTK2BMEN1HIF1A
SCHEMBL31643582 0.84 ALDH1A1 (0.71) KMT2AALDH1A1PTK2BMEN1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739303-B1 A NOVEL METHOD FOR PERORAL DELIVERY OF INSULIN AND ITS ANALOGUES FOR THERAPEUTIC USAGE TRANSGENE BIOTEK LTD (IN) 2020-04-01 EP claimed
US-20150051142-A1 NOVEL METHOD FOR PERORAL DELIVERY OF INSULIN AND ITS ANALOGUES FOR THERAPEUTIC USAGE TRANSGENE BIOTEK LTD (IN) 2015-02-19 US claimed
EP-2739303-A2 A NOVEL METHOD FOR PERORAL DELIVERY OF INSULIN AND ITS ANALOGUES FOR THERAPEUTIC USAGE Transgene Biotek Ltd. (IN) 2014-06-11 EP claimed
WO-2013021346-A2 A NOVEL METHOD FOR PERORAL DELIVERY OF INSULIN AND ITS ANALOGUES FOR THERAPEUTIC USAGE TRANSGENE BIOTEK LTD (IN) 2013-02-14 WO claimed
US-20040013734-A1 Mixture of water insoluble drug and polymer PFIZER INC. 2004-01-22 US claimed
EP-1027886-A2 Pharmaceutical solid dispersions Pfizer Products Inc. (US) 2000-08-16 EP claimed
US-20250281624-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES UNIVERSITY OF HOUSTON SYSTEM (US) 2025-09-11 US disclosed
EP-4419104-A2 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES University of Houston System (US) 2024-08-28 EP disclosed
CN-118284420-A Methods and compositions for treating chronic inflammatory lesions, metaplasias, dysplasias, and cancers of epithelial tissue 休斯敦大学体系 2024-07-02 CN disclosed
CN-114007671-B Methods and compositions for treating chronic inflammatory lesions, metaplasias, dysplasias, and cancers of epithelial tissue 休斯敦大学体系 2024-06-14 CN disclosed
WO-2023239422-A2 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES UNIVERSITY OF HOUSTON SYSTEM (US) 2023-12-14 WO disclosed
US-20230233691-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES UNIVERSITY OF HOUSTON SYSTEM (US) 2023-07-27 US disclosed
US-20230149295-A1 INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO UNIVERSITY OF HOUSTON SYSTEM (US) 2023-05-18 US disclosed
WO-1996011671-A1 TARGETED DELIVERY VIA BIODEGRADABLE POLYMERS FOCAL, INC. (US) 1996-04-25 WO disclosed
EP-0671906-A1 BIOADHESIVE MICROSPHERES AND THEIR USE AS DRUG DELIVERY AND IMAGING SYSTEMS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1995-09-20 EP disclosed
WO-1993021906-A9 BIOADHESIVE MICROSPHERES AND THEIR USE AS DRUG DELIVERY AND IMAGING SYSTEMS 1994-03-17 WO disclosed
US-5286763-A Polyanhydride and biacative molecular; nontoxic residues MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1994-02-15 US disclosed
WO-1993021906-A1 BIOADHESIVE MICROSPHERES AND THEIR USE AS DRUG DELIVERY AND IMAGING SYSTEMS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1993-11-11 WO disclosed
EP-0476045-A1 BIOERODIBLE POLYMERS FOR DRUG DELIVERY IN BONE. MASSACHUSETTS INST TECHNOLOGY (US) 1992-03-25 EP disclosed
WO-1990015586-A2 BIOERODIBLE POLYMERS FOR DRUG DELIVERY IN BONE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281624-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES FABP2, MYADM, FABP6 KMT2A 3663/4885ALDH1A1 306/4885PTK2B 1606/4885
US-20040013734-A1 Mixture of water insoluble drug and polymer ABCG2, ABCB1, ABCB11 KMT2A 3238/4885ALDH1A1 2151/4885PTK2B 1820/4885
US-20230233691-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES FABP2, MYADM, FABP6 KMT2A 3663/4885ALDH1A1 306/4885PTK2B 1606/4885
US-20230149295-A1 INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO EPCAM, FABP2, TPMT KMT2A 577/4885ALDH1A1 413/4885PTK2B 3922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.