Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513891 | 0.90 | ALOX5 (0.72) | ALOX5GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6633779 | 0.84 | ALOX5 (0.80) | ALOX5GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL17183577 | 0.84 | ALOX5 (0.64) | ALOX5GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL27627034 | 0.84 | ALOX5 (0.64) | ALOX5GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL17183532 | 0.82 | ALOX5 (0.62) | ALOX5GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL21596195 | 0.82 | ALOX5 (0.62) | ALOX5GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL21596219 | 0.82 | ALOX5 (0.62) | ALOX5GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11133887 | 0.82 | ALOX5 (0.77) | ALOX5GAARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL491040 | 0.81 | ALOX5 (0.70) | ALOX5GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4594453 | 0.81 | HDAC8 (0.68) | MAPTKDM4ECYP3A4HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4681828-A | Method of chemical electrographic image amplification using chemically active toner particles | EASTMAN KODAK COMPANY (US) | 1987-07-21 | — | — | US | claimed |
| US-4681828-A | Method of chemical electrographic image amplification using chemically active toner particles | EASTMAN KODAK COMPANY (US) | 1987-07-21 | — | — | US | disclosed |