SCHEMBL491040

SCHEMBL491040

O=C(O)CCC(=O)NNc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.70
L3MBTL1 Q9Y468 1/20 0.70
GAA P10253 7/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
LMNA P02545 2/20 0.54
CYP3A4 P08684 1/20 0.53
TSHR P16473 1/20 0.53
KDM4E B2RXH2 2/20 0.53
KMT2A Q03164 2/20 0.53
PTGS2 P35354 1/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1A2 P05177 1/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27627034 0.87 ALOX5 (0.64) ALOX5L3MBTL1GAASMN1; SMN2LMNA
SCHEMBL30513891 0.86 ALOX5 (0.72) ALOX5L3MBTL1GAASMN1; SMN2LMNA
SCHEMBL10117829 0.85 ALOX5 (0.71) ALOX5L3MBTL1GAASMN1; SMN2LMNA
SCHEMBL21055737 0.83 ALOX5 (0.63) ALOX5L3MBTL1GAASMN1; SMN2LMNA
SCHEMBL13042440 0.83 ALOX5 (0.68) ALOX5GAASMN1; SMN2LMNACYP3A4
SCHEMBL11418048 0.82 ALOX5 (0.73) ALOX5L3MBTL1GAASMN1; SMN2LMNA
SCHEMBL1531522 0.82 ALOX5 (1.00) ALOX5L3MBTL1GAASMN1; SMN2LMNA
SCHEMBL19720259 0.82 ALOX5 (0.62) ALOX5L3MBTL1GAASMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL28067312 0.82 ALOX5 (0.61) ALOX5L3MBTL1GAASMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL8957363 0.81 ALOX5 (0.96) ALOX5L3MBTL1GAASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119095925-A Two-component (2K) acrylic composition comprising biorenewable monomers 汉高股份有限及两合公司 2024-12-06 CN disclosed
CN-119095894-A Two-component (2K) acrylic composition comprising thermoplastic polyurethane 汉高股份有限及两合公司 2024-12-06 CN disclosed
WO-2023142013-A1 TWO-PART POLYURETHANE- (METH) ACRYLIC HYBRID ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2023-08-03 WO disclosed
CN-116323723-A Curing accelerators for anaerobically curable compositions 汉高股份有限及两合公司 2023-06-23 CN disclosed
CN-114667304-A One-component (1K) anaerobically curable compositions 汉高股份有限及两合公司 2022-06-24 CN disclosed
CN-111417693-B Curing accelerators for anaerobically curable compositions 汉高知识产权控股有限责任公司 2022-05-27 CN disclosed
CN-111417693-A Curing accelerators for anaerobically curable compositions 汉高知识产权控股有限责任公司 2020-07-14 CN disclosed
CN-107148411-B Phenylhydrazine/anhydride adducts and anaerobically curable compositions using phenylhydrazine/anhydride adducts 汉高知识产权控股有限责任公司 2020-06-19 CN disclosed
CN-106715559-B Curing accelerators for anaerobic curable compositions 汉高知识产权控股有限责任公司 2020-02-28 CN disclosed
EP-2285760-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2018-02-21 EP disclosed
WO-2009137448-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
WO-2009137448-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
WO-2009137444-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
WO-2009137444-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
EP-2097382-A1 HETEROARYL-SUBSTITUTED CARBOXAMIDES AND USE THEREOF FOR THE STIMULATION OF THE EXPRESSION OF NO SYNTHASE Sanofi-Aventis (FR) 2009-09-09 EP disclosed
WO-2008077507-A1 HETEROARYL-SUBSTITUTED CARBOXAMIDES AND USE THEREOF FOR THE STIMULATION OF THE EXPRESSION OF NO SYNTHASE SANOFI-AVENTIS (FR) 2008-07-03 WO disclosed
EP-1939181-A1 Heteroaryl-substituted carboxamides and use thereof for the stimulation of the expression of NO synthase sanofi-aventis (FR) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions ACLY, ACAD9, CCNY ALOX5 903/4885L3MBTL1 3534/4885GAA 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.